How tiny enzymes reign supreme in worldwide carbon recycling

After a tree falls in the forest and the chain saw has done its work, clusters of white-rot fungi appear near the cut surfaces. “Etherases” from these lowly fungi use the antioxidant glutathione to clip ether linkages in 23 milliseconds. Lewis and Wolfenden show that without these enzymes, the half-life for the needed hydrolysis of the ether linkages in lignin in water would be about 100 billion years, exceeding the age of the universe by a long shot.

So it turns out that these familiar organisms catalyze what is generally considered to be the rate-determining step in the global carbon cycle, using enzymes that are found to achieve the largest rate enhancement known for any of the thousands of enzymes that exist.

Without these little enzymes, we’d be in a world of hurt.

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